Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester
• CAS No.: 118110-21-7
• Molecular Formula: C₂₂H₁₈O₄S
• Molecular Weight: 378.449
• Mol file: 118110-21-7.mol

Synonyms:Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester

Chemical Property of Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester

There total 3 articles about Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-hydroxychalcone (644-78-0) + p-toluenesulfonyl chloride (98-59-9) → Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester (118110-21-7)

Guidance literature:

triethylamine; In 1,4-dioxane; at 25 ℃; for 0.25h;

DOI:10.1055/s-1988-27532

Reference yield: 55.0%

Methyl-carbamic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester (118110-06-8) + p-toluenesulfonyl chloride (98-59-9) → Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester (118110-21-7)

Guidance literature:

triethylamine; In 1,4-dioxane; for 2h; Heating;

DOI:10.1055/s-1988-27532

Reference yield:

2-hydroxychalcone (644-78-0) → Toluene-4-sulfonic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester (118110-21-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / (C₂H₅)3N / benzene / 0.67 h / Heating

2: 55 percent / (C₂H₅)3N / dioxane / 2 h / Heating

triethylamine; In 1,4-dioxane; benzene;

DOI:10.1055/s-1988-27532

upstream raw materials:

2-hydroxychalcone

p-toluenesulfonyl chloride

Methyl-carbamic acid 2-((E)-3-oxo-3-phenyl-propenyl)-phenyl ester