5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

Base Information

Chemical Name:5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile
CAS No.:868525-39-7
Molecular Formula:C₂₄H₂₂N₄OS
Molecular Weight:414.531
Hs Code.:

Synonyms:5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

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Chemical Property of 5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

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Technology Process of 5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

There total 1 articles about 5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 868525-07-9
5-mercapto isophthalonitrile

: 868525-18-2
2-((benzyloxy)methyl)-5-iodo-4-(trifluoromethyl)-1H-imidazole

: 868525-39-7
5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

Guidance literature:: 5-mercapto isophthalonitrile; With caesium carbonate; In acetonitrile; for 0.166667h; Heating / reflux;

2-((benzyloxy)methyl)-5-iodo-4-(trifluoromethyl)-1H-imidazole; copper(l) iodide; In acetonitrile; for 18h; Heating / reflux;

Reference yield: 35.0%

: 868525-39-7
5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

: 868525-03-5
5-(5-cyclopropyl-3-ethyl-2-hydroxymethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile

Guidance literature:: 5-(2-benzyloxymethyl-5-cyclopropyl-3-ethyl-3H-imidazol-4-ylsulfanyl)-isophthalonitrile; With boron trichloride - methyl sulfide complex; In dichloromethane; at 20 ℃; for 1h;

With sodium hydrogencarbonate; In dichloromethane; water;