methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside

Base Information

• Chemical Name: methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside
• CAS No.: 214767-60-9
• Molecular Formula: C₃₅H₃₆O₆
• Molecular Weight: 552.667
• Mol file: 214767-60-9.mol

Synonyms:methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside

Chemical Property of methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside

There total 5 articles about methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetic anhydride (108-24-7) + methyl 2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside (214767-59-6) → methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside (214767-60-9)

Guidance literature:

With pyridine; at 20 ℃; for 3h;

DOI:10.1016/S0968-0896(98)00127-8

Reference yield:

trityl chloride (76-83-5) → methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside (214767-60-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 16 h / 80 °C

2: 100 percent / pyridine / 3 h / 20 °C

With pyridine; In pyridine; 1: Alkylation / 2: Acetylation;

DOI:10.1016/S0968-0896(98)00127-8

Reference yield:

methyl 2-O-benzyl-3,6-dideoxy-α-D-ribo-hex-5-enopyranoside (214767-56-3) → methyl 4-O-acetyl-2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside (214767-60-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 66 percent / BH₃; H₂O₂ / dimethylformamide / 2 h / 50 °C

2: pyridine / 16 h / 80 °C

3: 100 percent / pyridine / 3 h / 20 °C

With pyridine; borane; dihydrogen peroxide; In pyridine; N,N-dimethyl-formamide; 1: Oxidation / 2: Alkylation / 3: Acetylation;

DOI:10.1016/S0968-0896(98)00127-8

upstream raw materials:

acetic anhydride

methyl 2-O-benzyl-3-deoxy-6-O-trityl-β-L-lyxo-hexopyranoside

trityl chloride

methyl 2-O-benzyl-3,6-dideoxy-α-D-ribo-hex-5-enopyranoside

Downstream raw materials:

methyl 4-O-acetyl-2-O-benzoyl-1-chloro-1,3-dideoxy-β-L-lyxo-hexopyranosyluronate

methyl 4-O-acetyl-2-O-benzyl-3-deoxy-β-L-lyxo-hexopyranoside