5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N¹-oxide

Base Information

• Chemical Name: 5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N¹-oxide
• CAS No.: 960308-96-7
• Molecular Formula: C₁₄H₁₀N₂O₂S
• Molecular Weight: 270.312
• Mol file: 960308-96-7.mol

Synonyms:5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N¹-oxide

Chemical Property of 5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N¹-oxide

Chemical Property:

Purity/Quality:

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Technology Process of 5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N¹-oxide

There total 1 articles about 5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N¹-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

phenylthiomethyl triphenylphosphonium chloride (13884-92-9) + 5-formylbenzo[c][1,2,5]oxadiazole 1-oxide (19164-42-2) → 5-(E)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide (960308-95-6) + 5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide (960308-96-7)

Guidance literature:

With potassium carbonate; 18-crown-6 ether; In toluene; for 2.5h; Heating;

DOI:10.1021/jm070604e

Reference yield: 58.0%

5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide (960308-96-7) → 5-(Z)-[2-(phenylsulfonyl)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide + 5-(E)-[2-(phenylsulfonyl)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide

Guidance literature:

With dihydrogen peroxide; acetic acid; for 0.333333h; Heating;

DOI:10.1021/jm070604e

Reference yield: 42.0%

5-(Z)-[2-(phenylthio)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide (960308-96-7) → 5-(Z)-[2-(phenylsulfonyl)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide + 5-(Z)-[2-(phenylsulfinyl)vinyl]benzo[1,2-c]-1,2,5-oxadiazole N1-oxide

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -78 - 20 ℃; for 2h;

DOI:10.1021/jm070604e

upstream raw materials:

phenylthiomethyl triphenylphosphonium chloride

5-formylbenzo[c][1,2,5]oxadiazole 1-oxide