(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Base Information

Chemical Name:(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester
CAS No.:168984-71-2
Molecular Formula:C₂₇H₄₃N₃O₉S₃
Molecular Weight:649.851
Hs Code.:

(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Synonyms:(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Suppliers and Price of (E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

There total 11 articles about (E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 168984-80-3
((E)-(S)-1-Benzyl-3-chlorosulfonyl-allyl)-carbamic acid tert-butyl ester

: (E)-(S)-3-((E)-(S)-3-Amino-but-1-ene-1-sulfonylamino)-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester; hydrochloride

: 168984-71-2
(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Guidance literature:: With dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 5h; Ambient temperature;

Reference yield:

: 79069-51-5
(S)-N-tert-butoxycarbonylvalinal

: 168984-71-2
(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 77 percent / nBuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

2: 3M HCl/MeOH / 3 h / Ambient temperature

3: 60 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU), 4-dimethylaminopyridine (DMAP) / CH₂Cl₂ / Ambient temperature

4: HCl/MeOH / 3 h / Ambient temperature; 0 to 25 deg C

5: 60 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU), 4-dimethylaminopyridine (DMAP) / CH₂Cl₂ / 5 h / Ambient temperature

With hydrogenchloride; methanol; dmap; n-butyllithium; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; hexane; dichloromethane;

Reference yield:

: 168984-79-0
(E)-(S)-3-tert-Butoxycarbonylamino-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

: 168984-71-2
(E)-(S)-3-[(E)-(S)-3-((E)-(S)-3-tert-Butoxycarbonylamino-4-phenyl-but-1-ene-1-sulfonylamino)-but-1-ene-1-sulfonylamino]-4-methyl-pent-1-ene-1-sulfonic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 3M HCl/MeOH / 3 h / Ambient temperature

2: 60 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU), 4-dimethylaminopyridine (DMAP) / CH₂Cl₂ / Ambient temperature

3: HCl/MeOH / 3 h / Ambient temperature; 0 to 25 deg C

4: 60 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU), 4-dimethylaminopyridine (DMAP) / CH₂Cl₂ / 5 h / Ambient temperature

With hydrogenchloride; methanol; dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane;