Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Base Information

Chemical Name:Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester
CAS No.:112166-29-7
Molecular Formula:C₈₄H₁₂₃NO₁₁
Molecular Weight:1322.9
Hs Code.:

Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Synonyms:Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Suppliers and Price of Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

There total 7 articles about Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 76-83-5
trityl chloride

: 112199-87-8
(R)-3-Benzyloxymethoxy-tetradecanoic acid (2R,3R,4R,5S,6R)-2-benzyloxy-3-((R)-3-dodecanoyloxy-tetradecanoylamino)-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yl ester

: 112166-29-7
Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Guidance literature:: In pyridine; at 90 ℃; for 6h;
DOI:10.1016/0008-6215(87)80220-3

Reference yield:

: 112-16-3
n-dodecanoyl chloride

: 112166-29-7
Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 95.3 percent / DMAP / CH₂Cl₂; pyridine / Ambient temperature

2: zinc dust, acetic acid / 50 °C

3: 90 percent / 3-(3-dimethylamino)propyl-1-ethylcarbodiimide hydrochloride / CH₂Cl₂ / Ambient temperature

4: 98.2 percent / 3-(3-dimethylamino)propyl-1-ethylcarbodiimide hydrochloride, 4-(dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

5: 94.5 percent / 95percent acetic acid

6: 99 percent / pyridine / 6 h / 90 °C

With dmap; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; zinc; In pyridine; dichloromethane;
DOI:10.1016/0008-6215(87)80220-3

Reference yield:

: 107856-74-6
C₂₆H₅₀O₄

: 112166-29-7
Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / 3-(3-dimethylamino)propyl-1-ethylcarbodiimide hydrochloride / CH₂Cl₂ / Ambient temperature

2: 98.2 percent / 3-(3-dimethylamino)propyl-1-ethylcarbodiimide hydrochloride, 4-(dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

3: 94.5 percent / 95percent acetic acid

4: 99 percent / pyridine / 6 h / 90 °C

With dmap; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In pyridine; dichloromethane;
DOI:10.1016/0008-6215(87)80220-3