tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

Base Information

Chemical Name:tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate
CAS No.:1264296-67-4
Molecular Formula:C₁₉H₂₀ClN₃O₂
Molecular Weight:357.84
Hs Code.:

Synonyms:tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

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Chemical Property of tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

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Technology Process of tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

There total 3 articles about tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1264296-66-3
C₁₂H₂₁NO₃

: 57999-09-4
5-amino-4-(4-chlorophenyl)-1Н-pyrazole

: 1264296-67-4
tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

Guidance literature:: With trifluoroacetic acid; In tert-butyl alcohol; at 60 ℃; for 1h;

Reference yield:

: 1694-31-1
tert-butyl acetoacetate

: 1264296-67-4
tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 0 - 20 °C

2: 3 h / 100 °C

3: trifluoroacetic acid / tert-butyl alcohol / 1 h / 60 °C

With potassium carbonate; trifluoroacetic acid; In acetone; tert-butyl alcohol;

Reference yield:

: 39149-65-0
tert-butyl 2-methyl-3-oxobutanoate

: 1264296-67-4
tert-butyl 2-(3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 3 h / 100 °C

2: trifluoroacetic acid / tert-butyl alcohol / 1 h / 60 °C

With trifluoroacetic acid; In tert-butyl alcohol;