(1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

Base Information

• Chemical Name: (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane
• CAS No.: 183446-14-2
• Molecular Formula: C₁₆H₂₁ClOTe
• Molecular Weight: 392.395
• Mol file: 183446-14-2.mol

Synonyms:(1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

Chemical Property of (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

There total 8 articles about (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(1S,2R,4R)-7,7-Dimethyl-1-phenyltellanylmethyl-bicyclo[2.2.1]heptan-2-ol (183446-24-4) → (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ4-tellura-tricyclo[5.2.1.01,5]decane (183446-14-2)

Guidance literature:

With pivaloyl chloride; In dichloromethane; at 0 ℃; for 0.333333h;

DOI:10.1016/0957-4166(96)00365-5

Reference yield: 83.0%

(1S,5R,7R)-3-Bromo-10,10-dimethyl-3-phenyl-4-oxa-3λ4-tellura-tricyclo[5.2.1.01,5]decane (183446-16-4) → (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ4-tellura-tricyclo[5.2.1.01,5]decane (183446-14-2)

Guidance literature:

With silver(I) chloride; In acetonitrile; for 16h; Ambient temperature;

Reference yield: 76.0%

(1S,5R,7R)-3-Fluoro-10,10-dimethyl-3-phenyl-4-oxa-3λ4-tellura-tricyclo[5.2.1.01,5]decane (183446-18-6) → (1S,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ4-tellura-tricyclo[5.2.1.01,5]decane (183446-14-2)

Guidance literature:

With sodium chloride; In acetonitrile; for 15h; Ambient temperature;

upstream raw materials:

(1S,2R,4R)-7,7-Dimethyl-1-phenyltellanylmethyl-bicyclo[2.2.1]heptan-2-ol

(1S,5R,7R)-3-Fluoro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

(1S,5R,7R)-3-Bromo-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

diphenyl ditelluride

Downstream raw materials:

(1S,5R,7R)-3-Fluoro-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

(1S,5R,7R)-3-Bromo-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane

(1S,5R,7R)-3-Iodo-10,10-dimethyl-3-phenyl-4-oxa-3λ⁴-tellura-tricyclo[5.2.1.0^1,5]decane