3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE

Base Information

• Chemical Name: 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE
• CAS No.: 61160-18-7
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Hs Code.: 2933399090
• Mol file: 61160-18-7.mol

Synonyms:2-Methyl-3-(benzyloxy)-4-pyridone;3-Benzyloxy-2-methyl-1H-pyridin-4-one;3-Benzyloxy-2-methyl-4(1H)pyridone;

Chemical Property of 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE

Chemical Property:

• Vapor Pressure: 2.85E-06mmHg at 25°C
• Melting Point: 171-173 °C
• Refractive Index: 1.589
• Boiling Point: 389.5 °C at 760 mmHg
• Flash Point: 189.3 °C
• PSA: 42.09000
• Density: 1.17 g/cm³
• LogP: 2.26230
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-(Benzyloxy)-2-methyl-4(1H)-pyridinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE

There total 13 articles about 3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

→ 3-benzyloxy-2-methyl-1H-pyridin-4-one (61160-18-7) + 3-benzyloxy-4-methoxypicolinic acid (170689-56-2)

Guidance literature:

Reference yield: 88.0%

3-O-benzylmaltol (61049-69-2) → 3-benzyloxy-2-methyl-1H-pyridin-4-one (61160-18-7)

Guidance literature:

With ammonium hydroxide; In ethanol; for 18h; Heating;

DOI:10.1021/jm00069a002

Reference yield:

Maltol (118-71-8) → 3-benzyloxy-2-methyl-1H-pyridin-4-one (61160-18-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / aq. NaOH / methanol / 16 h / Heating

2: 58 percent / aq. NH₃ / ethanol / 16 h / Heating

With ammonium hydroxide; sodium hydroxide; In methanol; ethanol;

DOI:10.1021/jm0504306

upstream raw materials:

3-O-benzylmaltol

Maltol

benzyl bromide

benzyl chloride

Downstream raw materials:

1-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-3-(benzyloxy)-2-methyl-4-pyridone

1-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)-3-(benzyloxy)-2-methyl-4-pyridone

3-(benzyloxy)-1-hexyl-2-methylpyridin-4(1H)-one

3-hydroxy-2-methylpyrid-4-one