Imidazo[1,2-A]pyrazin-8(7H)-one

Base Information

Chemical Name:Imidazo[1,2-A]pyrazin-8(7H)-one
CAS No.:434936-85-3
Molecular Formula:C₆H₅N₃O
Molecular Weight:135.125
Hs Code.:
European Community (EC) Number:953-279-4
DSSTox Substance ID:DTXSID30514908
Wikidata:Q82375483
Mol file:434936-85-3.mol

Synonyms:434936-85-3;IMIDAZO[1,2-A]PYRAZIN-8(7H)-ONE;IMIDAZO[1,2-A]PYRAZIN-8-OL;7H-IMIDAZO[1,2-A]PYRAZIN-8-ONE;SCHEMBL147129;DTXSID30514908;TQR0197;MCPSVGWMYIXRQE-UHFFFAOYSA-N;MFCD09834909;MFCD11846490;AKOS006282138;AKOS022171446;AB52830;AM806467;AS-39637;SY124562;CS-0035733;FT-0731732;EN300-74900;Z1259155946

Suppliers and Price of Imidazo[1,2-A]pyrazin-8(7H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
imidazo[1,2-a]pyrazin-8-ol
100mg
$ 90.00

TRC
imidazo[1,2-a]pyrazin-8-ol
50mg
$ 45.00

Crysdot
Imidazo[1,2-a]pyrazin-8(7H)-one 95+%
10g
$ 1126.00

Crysdot
Imidazo[1,2-a]pyrazin-8-ol 95+%
1g
$ 386.00

Crysdot
Imidazo[1,2-a]pyrazin-8(7H)-one 95+%
5g
$ 842.00

American Custom Chemicals Corporation
IMIDAZO[1,2-A]PYRAZIN-8-(7H)-ONE 95.00%
5MG
$ 503.78

AK Scientific
Imidazo[1,2-a]pyrazin-8-ol
25g
$ 2244.80

AK Scientific
Imidazo[1,2-a]pyrazin-8-ol
5g
$ 873.20

Total 12 raw suppliers

Chemical Property of Imidazo[1,2-A]pyrazin-8(7H)-one

Chemical Property:

Refractive Index:1.738
PKA:10.23±0.20(Predicted)
Density:1.51 g/cm³
Storage Temp.:2-8°C
XLogP3:-0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:135.043261791
Heavy Atom Count:10
Complexity:189

Purity/Quality:

99%, ^*data from raw suppliers

imidazo[1,2-a]pyrazin-8-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C=CN=C2C(=O)N1

Technology Process of Imidazo[1,2-A]pyrazin-8(7H)-one

There total 1 articles about Imidazo[1,2-A]pyrazin-8(7H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 434936-84-2
1-(2,2-diethoxyethyl)-1H-imidazole-2-carboxamide

: 434936-85-3
Imidazo[1,2-a]pyrazin-8(7H)-one

Guidance literature:: With hydrogenchloride; In water; for 3h; Heating;
DOI:10.1002/1522-2675(200202)85:2<502::AID-HLCA502>3.0.CO;2-L

Reference yield: 19.0%

: 459-46-1
4-Fluorobenzyl bromide

: 434936-85-3
Imidazo[1,2-a]pyrazin-8(7H)-one

: 7-(4-fluorobenzyl)imidazo[1,2-a]pyrazin-8(7H)-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.75h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.8b01578

Reference yield:

: 434936-85-3
Imidazo[1,2-a]pyrazin-8(7H)-one

: 434936-88-6
7-{2'-deoxy-5'-O-[(4,4'-dimethoxytriphenyl)methyl]-β-D-ribofuranosyl}imidazo[1,2-a]pyrazin-8(7H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: N,O-bis(trimethylsilyl)acetamide / acetonitrile / 0.5 h / 20 °C

1.2: 62 percent / SnCl₄ / 3.5 h / 0 - 20 °C

2.1: 100 percent / cc. NH₃ / ethanol / -30 - 20 °C

3.1: 35 percent / pyridine / 2 h / 0 - 20 °C

With N,O-bis-(trimethylsilyl)-acetamide; ammonia; In pyridine; ethanol; acetonitrile;
DOI:10.1002/1522-2675(200202)85:2<502::AID-HLCA502>3.0.CO;2-L