N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Base Information

Chemical Name:N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide
CAS No.:1374744-75-8
Molecular Formula:C₂₀H₁₅F₃N₄O₂S
Molecular Weight:432.426
Hs Code.:

Synonyms:N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

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Technology Process of N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

There total 5 articles about N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₂₃F₃N₄O₄S

: 1374744-75-8
N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Guidance literature:: C₂₅H₂₃F₃N₄O₄S; With trifluoroacetic acid; In dichloromethane; for 1h;

With sodium hydrogencarbonate; In dichloromethane;
DOI:10.1016/j.bmc.2012.06.018

Reference yield:

: 893-33-4
4,4,4-trifluoro-1-(2-naphthyl)-1,3-butanedione

: 1374744-75-8
N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride / ethanol / Reflux

2: platinum(IV) oxide; hydrogen / ethanol

3: triethylamine / dichloromethane / 1 h / 25 °C

4: trifluoroacetic acid / dichloromethane / 1 h

With hydrogenchloride; platinum(IV) oxide; hydrogen; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1016/j.bmc.2012.06.018

Reference yield:

: C₂₀H₁₂F₃N₃O₂

: 1374744-75-8
N-[4-(5-naphthalen-2-yl-3-trifluoromethyl-pyrazol-1-yl)-phenyl]-aminosulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: platinum(IV) oxide; hydrogen / ethanol

2: triethylamine / dichloromethane / 1 h / 25 °C

3: trifluoroacetic acid / dichloromethane / 1 h

With platinum(IV) oxide; hydrogen; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1016/j.bmc.2012.06.018