2,5-Dibromo-4-iodotoluene

Base Information

• Chemical Name: 2,5-Dibromo-4-iodotoluene
• CAS No.: 123568-21-8
• Molecular Formula: C₇H₅Br₂I
• Molecular Weight: 375.829
• Mol file: 123568-21-8.mol

Synonyms:2,5-Dibromo-4-iodotoluene

Chemical Property of 2,5-Dibromo-4-iodotoluene

Chemical Property:

• Boiling Point: 316.5±42.0 °C(Predicted)
• Density: 2.346±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

1,4-Dibromo-2-iodo-5-methylbenzene 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-Dibromo-4-iodotoluene

There total 1 articles about 2,5-Dibromo-4-iodotoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

4-tolyl iodide (624-31-7) → 2,5-Dibromo-4-iodotoluene (123568-21-8)

Guidance literature:

With bromine; iron(III) chloride; In tetrachloromethane; Heating;

DOI:10.1021/jo00288a013

Reference yield: 81.0%

2,5-Dibromo-4-iodotoluene (123568-21-8) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → Methyl (E)-4-Methyl-2,5-dibromocinnamate (123568-23-0)

Guidance literature:

With triethylamine; palladium diacetate; at 100 ℃; for 16.5h;

DOI:10.1021/jo00288a013

Reference yield: 71.0%

2-hydroxy-3-butene (598-32-3) + 2,5-Dibromo-4-iodotoluene (123568-21-8) → 4-(2,5-Dibromo-4-methylphenyl)-2-butanone (123568-35-4)

Guidance literature:

With triethylamine; palladium diacetate; In acetonitrile; at 100 ℃; for 18h;

DOI:10.1021/jo00288a013

upstream raw materials:

4-tolyl iodide

Downstream raw materials:

4-(2,5-Dibromo-4-methylphenyl)-2-butanone

Methyl (E)-4-Methyl-2,5-dibromocinnamate

2-(4-methyl-2,5-bis-trimethylsilanylethynyl-phenyl)-thiophene

4-[5-(2,5-diethynyl-4-methyl-phenyl)-thiophen-2-yl]-2-hydroxy-benzaldehyde