kaitocephalin

Base Information

Chemical Name:kaitocephalin
CAS No.:433232-07-6
Molecular Formula:C₁₈H₂₁Cl₂N₃O₉
Molecular Weight:494.285
Hs Code.:

Synonyms:kaitocephalin

Suppliers and Price of kaitocephalin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of kaitocephalin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of kaitocephalin

There total 40 articles about kaitocephalin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: (1S,5R,7aR)-1-((S)-Amino-carboxy-methyl)-5-[(S)-2-(3,5-dichloro-4-hydroxy-benzoylamino)-2-methoxycarbonyl-ethyl]-3-oxo-dihydro-pyrrolo[1,2-c]oxazole-7a-carboxylic acid methyl ester

: 433232-07-6
kaitocephalin

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; water; at 40 ℃; for 18h;
DOI:10.1021/ja016403w

Reference yield: 30.0%

: 433238-69-8
(2R,5R)-2-((1S,2S)-2-Benzyloxycarbonylamino-2-carboxy-1-hydroxy-ethyl)-5-[(S)-2-benzyloxycarbonyl-2-(4-benzyloxy-3,5-dichloro-benzoylamino)-ethyl]-pyrrolidine-1,2-dicarboxylic acid dibenzyl ester

: 433232-07-6
kaitocephalin

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; chloroform; at 20 ℃;
DOI:10.1016/S0040-4039(01)02254-7

Reference yield:

: (2R,5R)-5-[(R)-3-(tert-Butyl-diphenyl-silanyloxy)-2-methanesulfonyloxy-propyl]-2-((1S,2R)-1,3-diacetoxy-2-tert-butoxycarbonylamino-propyl)-pyrrolidine-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

: 433232-07-6
kaitocephalin

Guidance literature:: Multi-step reaction with 12 steps

1: 619 mg / TBAF; AcOH / tetrahydrofuran / 1 h / 20 °C

2: 100 percent / H₂ / PtO₂ / ethyl acetate / atmospheric pressure

3: aq. H₂SO₄; CrO₃ / acetone / 0.67 h / 20 °C

4: 472 mg / tetrahydrofuran; diethyl ether / 10 h

5: 78 percent / Mg; methanol / 2 h / 35 - 40 °C

6: sodium azide / dimethylformamide / 7 h / 20 °C

7: H₂ / Pd/C / methanol / atmospheric pressure

8: triethylamine / CH₂Cl₂ / 20 °C

9: 117 mg / aq. H₂SO₄; CrO₃ / acetone / 0.67 h / 20 °C

10: 100 percent / H₂ / Pd/C / methanol / 0.5 h / 760.05 Torr

11: 100 percent / HCl / methanol; H₂O / 1 h

12: 92 percent / NaOH / H₂O; methanol; tetrahydrofuran / 18 h / 40 °C

With chromium(VI) oxide; hydrogenchloride; methanol; sodium hydroxide; sodium azide; sulfuric acid; tetrabutyl ammonium fluoride; hydrogen; magnesium; acetic acid; triethylamine; platinum(IV) oxide; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetone; 3: Jones oxidation / 9: Jones oxidation;
DOI:10.1021/ja016403w