Technology Process of (3,5-dimethoxyphenyl) 7-hydroxyhexyl ketone
There total 10 articles about (3,5-dimethoxyphenyl) 7-hydroxyhexyl ketone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dimethyl zinc(II); titanium tetrachloride;
In
dichloromethane;
at -30 - 20 ℃;
for 6h;
Inert atmosphere;
DOI:10.1039/C6OB02796B
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / 12 h / 20 °C / Inert atmosphere
2: hydrogen / ethyl acetate / 2 h / 20 °C
3: titanium tetrachloride; dimethyl zinc(II) / dichloromethane / 6 h / -30 - 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; hydrogen; dimethyl zinc(II); titanium tetrachloride; triethylamine;
In
dichloromethane; ethyl acetate;
1: |Sonogashira Cross-Coupling;
DOI:10.1039/C6OB02796B
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / 12 h / 20 °C / Inert atmosphere
2: hydrogen / ethyl acetate / 2 h / 20 °C
3: titanium tetrachloride; dimethyl zinc(II) / dichloromethane / 6 h / -30 - 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; hydrogen; dimethyl zinc(II); titanium tetrachloride; triethylamine;
In
dichloromethane; ethyl acetate;
1: |Sonogashira Cross-Coupling;
DOI:10.1039/C6OB02796B
