Inolitazone

Base Information

• Chemical Name: Inolitazone
• CAS No.: 223132-37-4
• Molecular Formula: C27H26 N4 O4 S
• Molecular Weight: 502.594
• UNII: M17ILL71MC
• DSSTox Substance ID: DTXSID60944956
• Nikkaji Number: J3.098.946E
• Wikidata: Q21083321
• NCI Thesaurus Code: C83819
• Pharos Ligand ID: YKJ96YVPM7JZ
• Metabolomics Workbench ID: 152977
• ChEMBL ID: CHEMBL3545280
• Mol file: 223132-37-4.mol

Synonyms:CS 7017;CS-7017;CS7017;efatutazone;efatutazone hydrochloride;RS 5444;RS-5444;RS5444

Chemical Property of Inolitazone

Chemical Property:

• Boiling Point: 765.7±60.0 °C(Predicted)
• PKA: 6.34±0.50(Predicted)
• PSA: 144.63000
• Density: 1.39
• LogP: 5.93730
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 502.16747650
• Heavy Atom Count: 36
• Complexity: 782

Purity/Quality:

97% ^*data from raw suppliers

Inolitazone 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1N)C)OC2=CC3=C(C=C2)N=C(N3C)COC4=CC=C(C=C4)CC5C(=O)NC(=O)S5
• Recent ClinicalTrials: Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery
• Recent NIPH Clinical Trials: Phase 1 Study of CS-7017

Technology Process of Inolitazone

There total 4 articles about Inolitazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-{4-[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl}thiazolidine-2,4-dione dihydrochloride → 5-{4-[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl}thiazolidine-2,4-dione (223132-37-4)

Guidance literature:

With water; at 80 ℃; for 1h; Product distribution / selectivity;

Reference yield:

t-Butyl N-{2-[4-(2,4-Dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-(4-t-butoxycarbonylamino-3,5-dimethylphenoxy)phenyl}-N-methylcarbamate → 5-{4-[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl}thiazolidine-2,4-dione (223132-37-4)

Guidance literature:

With hydrogenchloride;

Reference yield:

t-butyl N-[5-(4-t-butoxycarbonylamino-3,5-dimethylphenoxy)-2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]phenyl]-N-methylcarbamate → 5-{4-[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl}thiazolidine-2,4-dione (223132-37-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 23h;

Downstream raw materials:

rac-5-[(p-{[6-(4-amino-3,5-xylyloxy)-1-methyl-1,3-diaza-1H-inden-2-yl]methoxy}phenyl)methyl]-(5-²H)-1,3-thiazolidine-2,4-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 223132-37-4 inolitazone

Send

Send

Metric Ton KG G Pound L ML

Send

Send