Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

Base Information

Chemical Name:Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide
CAS No.:397850-36-1
Molecular Formula:C₄₂H₅₇N₅O
Molecular Weight:647.947
Hs Code.:

Synonyms:Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

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Chemical Property of Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

Chemical Property:

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Technology Process of Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

There total 3 articles about Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: NaHCO₃(s)

: 397850-40-7
N-(2-aminoethyl)-N'-(6-biphenyl-3-yl-pyrimidin-4-yl)-N-ethyl-benzene-1,4,-diamine

: 19117-92-1
α-chloro-palmitic acid

: 397850-36-1
Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; ethyl acetate;

Reference yield:

: 397851-03-5
N-(6-biphenyl-3-yl-pyrimidin-4-yl)-N'-(2-chloroethyl)-N'-ethyl-benzene-1,4-diamine

: 397850-36-1
Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

2: hydrogenchloride; hydrazine hydrate / ethanol; water

3: N-ethyl-N,N-diisopropylamine / 1,4-dioxane; ethyl acetate

With hydrogenchloride; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; ethanol; water; ethyl acetate;

Reference yield:

: 397851-04-6
2-[[4-[(6-[1,1'-biphenyl]-3-yl-4-pyrimidinyl)amino]phenyl]ethylamino]-ethanol

: 397850-36-1
Hexadecanoic acid (2-{[4-(6-biphenyl-3-yl-pyrimidin-4-yl-amino)-phenyl]-ethyl-amino}-ethyl)-amide

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / dichloromethane

3: hydrogenchloride; hydrazine hydrate / ethanol; water

4: N-ethyl-N,N-diisopropylamine / 1,4-dioxane; ethyl acetate

With hydrogenchloride; thionyl chloride; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; ethanol; dichloromethane; water; ethyl acetate;