Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester

Base Information

• Chemical Name: Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester
• CAS No.: 85166-79-6
• Molecular Formula: C₁₃H₂₁O₆PS
• Molecular Weight: 336.346
• Mol file: 85166-79-6.mol

Synonyms:Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester

Chemical Property of Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester

There total 3 articles about Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Methanesulfinic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester (85166-80-9) → Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester (85166-79-6)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/ja00347a054

Reference yield:

diethyl 1-hydroxy-1-phenylethylphosphonate (34881-11-3) → Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester (85166-79-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

2: 91 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 2 h / Ambient temperature

With triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1021/ja00347a054

Reference yield:

Diethyl-α,α-methyltrimethylsiloxybenzylphosphonat (54599-18-7) → Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester (85166-79-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / trifluoroacetic acid / methanol

2: 91 percent / triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

3: 91 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 2 h / Ambient temperature

With triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1021/ja00347a054

upstream raw materials:

Methanesulfinic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester

diethyl 1-hydroxy-1-phenylethylphosphonate

Diethyl-α,α-methyltrimethylsiloxybenzylphosphonat

Downstream raw materials:

diethyl (1-phenylethenyl)phosphonate

Acetic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester

(1-Ethoxy-1-phenyl-ethyl)-phosphonic acid diethyl ester

(1-Methoxy-1-phenyl-ethyl)-phosphonic acid diethyl ester