Technology Process of C24H24N4O2
There total 4 articles about C24H24N4O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-[(4-cyanophenyl)methyl]-3-[3-(acetamidomethyl)phenyl]benzamide;
With
hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine;
In
methanol;
at 65 ℃;
for 18h;
With
acetic anhydride;
In
acetic acid;
at 20 ℃;
for 0.5h;
With
palladium 10% on activated carbon; hydrogen;
In
acetic acid;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 72 h / 20 °C
2.1: sodium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; 1,4-dioxane / 0.33 h / 150 °C / Microwave irradiation
3.1: hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine / methanol / 18 h / 65 °C
3.2: 0.5 h / 20 °C
3.3: 20 °C
With
tetrakis(triphenylphosphine) palladium(0); hydroxylamine hydrochloride; sodium carbonate; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; methanol; dichloromethane; water;
2.1: |Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; 1,4-dioxane / 0.33 h / 150 °C / Microwave irradiation
2.1: hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine / methanol / 18 h / 65 °C
2.2: 0.5 h / 20 °C
2.3: 20 °C
With
tetrakis(triphenylphosphine) palladium(0); hydroxylamine hydrochloride; sodium carbonate; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; methanol; water;
1.1: |Suzuki Coupling;