1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea

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Chemical Name:1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea
CAS No.:1202884-52-3
Molecular Formula:C₂₆H₃₀N₈O₂
Molecular Weight:486.577
Hs Code.:

Synonyms:1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea

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Chemical Property of 1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea

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Technology Process of 1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea

There total 2 articles about 1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 462-08-8
pyridin-3-ylamine

: 32315-10-9
bis(trichloromethyl) carbonate

: 1202884-51-2
4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo-[2,3-d]pyrimidin-2-yl}aniline

: 1202884-52-3
1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea

: 1202884-53-4
7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-N-pyridin-3-yl-2-{4-[(pyridin-3-ylcarbamoyl)amino]phenyl}-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide

Guidance literature:: bis(trichloromethyl) carbonate; 4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo-[2,3-d]pyrimidin-2-yl}aniline; With triethylamine; In chloroform; at 20 ℃; for 0.25h;

pyridin-3-ylamine; In chloroform; at 20 ℃;

Reference yield: 45.0%

: 462-08-8
pyridin-3-ylamine

: 32315-10-9
bis(trichloromethyl) carbonate

: 1202884-51-2
4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo-[2,3-d]pyrimidin-2-yl}aniline

: 1202884-52-3
1-(4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-pyridin-3-ylurea

Guidance literature:: bis(trichloromethyl) carbonate; 4-{7-[2-(dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo-[2,3-d]pyrimidin-2-yl}aniline; With triethylamine; In chloroform; at 20 ℃; for 0.25h;

pyridin-3-ylamine; In chloroform; at 20 ℃;
DOI:10.1021/jm901783v