5,6-Dichloroindolin-2-one

Base Information

Chemical Name:5,6-Dichloroindolin-2-one
CAS No.:71293-59-9
Molecular Formula:C8H5Cl2NO
Molecular Weight:202.0374
Hs Code.:2933790090
DSSTox Substance ID:DTXSID30449246
Nikkaji Number:J997.405I
Wikidata:Q72465988
Mol file:71293-59-9.mol

Synonyms:5,6-Dichloroindolin-2-one;71293-59-9;5,6-DICHLORO-2,3-DIHYDRO-1H-INDOL-2-ONE;5,6-dichloro-1,3-dihydroindol-2-one;2H-INDOL-2-ONE, 5,6-DICHLORO-1,3-DIHYDRO-;5,6-DICHLORO-2-OXINDOLE;5,6-DICHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE;5,6-dichlorooxindole;2H-Indol-2-one,5,6-dichloro-1,3-dihydro-;5,6-Dichloroindoline-2-one;SCHEMBL5441646;DTXSID30449246;WCA29359;MFCD08692699;AKOS000276785;PB34325;AS-33204;CS-0050728;FT-0651671;A837145;J-516514

Suppliers and Price of 5,6-Dichloroindolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5,6-Dichloroindolin-2-one
100mg
$ 60.00

TRC
5,6-Dichloroindolin-2-one
50mg
$ 45.00

TRC
5,6-Dichloroindolin-2-one
500mg
$ 90.00

SynQuest Laboratories
5,6-Dichloro-1,3-dihydroindol-2-one
1 g
$ 83.00

SynQuest Laboratories
5,6-Dichloro-1,3-dihydroindol-2-one
5 g
$ 300.00

SynQuest Laboratories
5,6-Dichloro-1,3-dihydroindol-2-one
25 g
$ 1100.00

Medical Isotopes, Inc.
5,6-Dichloroindolin-2-one 95+%
1 g
$ 585.00

Matrix Scientific
5,6-Dichloroindolin-2-one >95%
5g
$ 1876.00

Matrix Scientific
5,6-Dichloroindolin-2-one >95%
1g
$ 511.00

Crysdot
5,6-Dichloroindolin-2-one 95+%
5g
$ 257.00

Total 32 raw suppliers

Chemical Property of 5,6-Dichloroindolin-2-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:209-210℃
Refractive Index:1.615
Boiling Point:365.143 °C at 760 mmHg
PKA:12.19±0.20(Predicted)
Flash Point:174.633 °C
PSA：29.10000
Density:1.497 g/cm³
LogP:2.62600
Storage Temp.:2-8°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:200.9748192
Heavy Atom Count:12
Complexity:209

Purity/Quality:

99%, ^*data from raw suppliers

5,6-Dichloroindolin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=CC(=C(C=C2NC1=O)Cl)Cl

Technology Process of 5,6-Dichloroindolin-2-one

There total 5 articles about 5,6-Dichloroindolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 215959-21-0
2-(4,5-Dichloro-2-nitro-phenyl)-malonic acid diethyl ester

: 71293-59-9
5,6-dichloroindol-2-one

Guidance literature:: With hydrogenchloride; tin; In ethanol; Heating;
DOI:10.1016/S0040-4039(98)01719-5

Reference yield: 76.0%

: 286949-63-1
4,5-dichloro-2-nitrophenylacetic acid methyl ester

: 71293-59-9
5,6-dichloroindol-2-one

Guidance literature:: With hydrogen; acetic acid; platinum(IV) oxide; at 20 ℃; for 20h; under 2068.65 Torr;
DOI:10.1021/jm990320x

Reference yield:

: 37777-90-5
2-nitro-4,5-dichlorophenylacetic acid

: 71293-59-9
5,6-dichloroindol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / concd H₂SO₄ / 7 h / Heating

2: 76 percent / H₂; AcOH / PtO₂ / 20 h / 20 °C / 2068.65 Torr

With sulfuric acid; hydrogen; acetic acid; platinum(IV) oxide; 1: Esterification / 2: Reduction;
DOI:10.1021/jm990320x