(R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

Base Information

Chemical Name:(R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone
CAS No.:139192-57-7
Molecular Formula:C₂₀H₂₉NO₄S
Molecular Weight:379.521
Hs Code.:

Synonyms:(R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

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Chemical Property of (R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

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Technology Process of (R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

There total 3 articles about (R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 930-91-6
2-hydroxymethylenecyclopentanone

: 139192-50-0
(2S)-N-(2,4,6-trimethylbenzenesulfonyl)-2-amino-3-methyl-butanol

: 139192-66-8
(S)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

: 139192-57-7
(R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

Guidance literature:: With methanesulfonic acid; 4 A molecular sieve; In dichloromethane; at 25 ℃; for 24h;
DOI:10.1055/s-1991-28410

Reference yield:

: 773-64-8
2-mesitylenesulphonyl chloride

: 139192-57-7
(R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / CH₂Cl₂ / 24 h / 0 °C

2: 28 percent / methanesulfonic acid, molecular sieves 4 Angstroem / CH₂Cl₂ / 24 h / 25 °C

With methanesulfonic acid; 4 A molecular sieve; triethylamine; In dichloromethane;
DOI:10.1055/s-1991-28410

Reference yield:

: 2026-48-4,473-75-6
(S)-valinol

: 139192-57-7
(R)-2-[(2S,4S)-4-Isopropyl-3-(2,4,6-trimethyl-benzenesulfonyl)-oxazolidin-2-yl]-cyclopentanone

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / CH₂Cl₂ / 24 h / 0 °C

2: 28 percent / methanesulfonic acid, molecular sieves 4 Angstroem / CH₂Cl₂ / 24 h / 25 °C

With methanesulfonic acid; 4 A molecular sieve; triethylamine; In dichloromethane;
DOI:10.1055/s-1991-28410