(R)-2-Amino-1-propane

Base Information

Chemical Name:(R)-2-Amino-1-propane
CAS No.:74474-93-4
Molecular Formula:C₁₇H₂₂N₂
Molecular Weight:254.375
Hs Code.:

(R)-2-Amino-1-<bis(phenylmethyl)amino>propane

Synonyms:(R)-2-Amino-1-propane

Suppliers and Price of (R)-2-Amino-1-propane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-Amino-1-propane

Chemical Property:

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Technology Process of (R)-2-Amino-1-propane

There total 6 articles about (R)-2-Amino-1-propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 674792-11-1
(R)-2-Amino-N,N-dibenzyl-propionamide

: 74474-93-4
(R)-2-Amino-1-propane

Guidance literature:: With dimethylsulfide borane complex; Ambient temperature;
DOI:10.1016/0957-4166(94)00341-8

Reference yield:

: 162150-51-8
(R)-<2--1-methyl-2-oxoethyl>carbamic acid 1,1-dimethylethyl ester

: 74474-93-4
(R)-2-Amino-1-propane

Guidance literature:: Multi-step reaction with 2 steps

1: TFA / CH₂Cl₂ / 1.) 0 deg C; 2.) room temp.

2: 1.) BH₃-DMS; 2.) 50percent aq. KOH / 1.) THF, room temp., 2.) reflux

With potassium hydroxide; dimethylsulfide borane complex; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jo00118a039

Reference yield:

: 103-49-1
dibenzylamine

: 74474-93-4
(R)-2-Amino-1-propane

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

2.1: trifluoroacetic acid / dichloromethane

3.1: borane-THF

3.3: Reflux

With 4-methyl-morpholine; borane-THF; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2011.02.090