(R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

Base Information

Chemical Name:(R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate
CAS No.:1239355-51-1
Molecular Formula:C₂₅H₂₂ClF₃N₂O₅
Molecular Weight:522.908
Hs Code.:

Synonyms:(R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

Suppliers and Price of (R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

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Technology Process of (R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

There total 1 articles about (R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 788814-15-3
(R)-ethyl 2-amino-3-(benzyloxy)propanoate

: 1239355-60-2
2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinic acid

: 1239355-51-1
(R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 18h;

Reference yield: 74.0%

: 1239355-51-1
(R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate

: 1239355-52-2
(R)-3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoic acid

Guidance literature:: (R)-ethyl 3-(benzyloxy)-2-(2-(2-chloro-4-(trifluoromethyl)phenoxy)nicotinamido)propanoate; With sodium hydroxide; In methanol; at 20 ℃; for 18h;

With hydrogenchloride; In water; pH=3;