Technology Process of 5,5'-Bis-[(E)-2-(2,5-bis-decyl-4-iodo-phenyl)-vinyl]-[2,2']bipyridinyl
There total 8 articles about 5,5'-Bis-[(E)-2-(2,5-bis-decyl-4-iodo-phenyl)-vinyl]-[2,2']bipyridinyl which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 73 percent / NiBr2(PPh3)2, Zn, Et4NI / tetrahydrofuran / 20 h / 50 °C
2: 38 percent / NBS
3: 82 percent
4: 1.) NaH / 1.) 1,2-dimethoxyethane, RT, 10 min, 2.) 1,2-dimethoxyethane, reflux, overnight
With
dibromobis(triphenylphosphine)nickel(II); N-Bromosuccinimide; tetraethylammonium iodide; sodium hydride; zinc;
In
tetrahydrofuran;
DOI:10.1021/ja9825130
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Mg, 2.) PdCl2(dppf) / 1.) ether, reflux, 0.5 h, 2.) ether, reflux, overnight
2: 75 percent / iodine, H5IO6, acetic acid, 30 percent sulfuric acid / CHCl3 / 48 h / 80 °C
3: 1.) n-BuLi / 1.) ether, hexane, 0 deg C, 2.) ether, hexane, RT, 2 h
4: 1.) NaH / 1.) 1,2-dimethoxyethane, RT, 10 min, 2.) 1,2-dimethoxyethane, reflux, overnight
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; n-butyllithium; sulfuric acid; iodine; sodium hydride; magnesium; acetic acid; periodic acid;
In
chloroform;
DOI:10.1021/ja9825130
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Mg, 2.) PdCl2(dppf) / 1.) ether, reflux, 0.5 h, 2.) ether, reflux, overnight
2: 75 percent / iodine, H5IO6, acetic acid, 30 percent sulfuric acid / CHCl3 / 48 h / 80 °C
3: 1.) n-BuLi / 1.) ether, hexane, 0 deg C, 2.) ether, hexane, RT, 2 h
4: 1.) NaH / 1.) 1,2-dimethoxyethane, RT, 10 min, 2.) 1,2-dimethoxyethane, reflux, overnight
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; n-butyllithium; sulfuric acid; iodine; sodium hydride; magnesium; acetic acid; periodic acid;
In
chloroform;
DOI:10.1021/ja9825130
