Technology Process of (2S,3S)-1-Amino-2,3-diphenyl-cyclopropanecarboxylic acid
There total 7 articles about (2S,3S)-1-Amino-2,3-diphenyl-cyclopropanecarboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
tetrachloromethane;
at 25 ℃;
for 0.5h;
DOI:10.1021/ja981153d
- Guidance literature:
-
Multi-step reaction with 7 steps
1: SOCl2 / CCl4 / 0.5 h / Heating
2: aq. NaIO4, RuCl3 / CCl4; acetonitrile / 1 h / Ambient temperature
3: 1.) NaH / 1.) DME, 2.) DME, RT, 2 h
4: aq. NaIO4, RuCl3 / acetonitrile; chlorosulfonic acid / 15 h / Ambient temperature
5: 50 percent / diphenylphosphoryl azide, Et3N / 15 h / Heating
6: 95 percent / aq. NaOH / methanol / 48 h / Heating
7: TFA / CCl4 / 0.5 h / 25 °C
With
ruthenium trichloride; sodium hydroxide; sodium periodate; thionyl chloride; diphenylphosphoranyl azide; sodium hydride; triethylamine; trifluoroacetic acid;
In
methanol; tetrachloromethane; chlorosulfonic acid; acetonitrile;
DOI:10.1021/ja981153d
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) NaH / 1.) DME, 2.) DME, RT, 2 h
2: aq. NaIO4, RuCl3 / acetonitrile; chlorosulfonic acid / 15 h / Ambient temperature
3: 50 percent / diphenylphosphoryl azide, Et3N / 15 h / Heating
4: 95 percent / aq. NaOH / methanol / 48 h / Heating
5: TFA / CCl4 / 0.5 h / 25 °C
With
ruthenium trichloride; sodium hydroxide; sodium periodate; diphenylphosphoranyl azide; sodium hydride; triethylamine; trifluoroacetic acid;
In
methanol; tetrachloromethane; chlorosulfonic acid; acetonitrile;
DOI:10.1021/ja981153d
