Benzo[b]furan-3-ylacetyl chloride

Base Information

Chemical Name:Benzo[b]furan-3-ylacetyl chloride
CAS No.:857283-98-8
Molecular Formula:C₁₀H₇ClO₂
Molecular Weight:194.617
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70428737
Wikidata:Q82241551
Mol file:857283-98-8.mol

Synonyms:Benzo[b]furan-3-ylacetyl chloride;857283-98-8;2-(1-benzofuran-3-yl)acetyl chloride;2-(Benzofuran-3-yl)acetyl chloride;DTXSID70428737;AKOS006343727;FT-0656894;A841433;J-519694

Suppliers and Price of Benzo[b]furan-3-ylacetyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BENZO[B]FURAN-3-YLACETYL CHLORIDE 95.00%
1G
$ 781.24

American Custom Chemicals Corporation
BENZO[B]FURAN-3-YLACETYL CHLORIDE 95.00%
250MG
$ 661.91

Total 9 raw suppliers

Chemical Property of Benzo[b]furan-3-ylacetyl chloride

Chemical Property:

Vapor Pressure:0.00218mmHg at 25°C
Refractive Index:1.604
Boiling Point:289.6 °C at 760 mmHg
Flash Point:128.9 °C
PSA：30.21000
Density:1.317 g/cm³
LogP:2.74070
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:194.0134572
Heavy Atom Count:13
Complexity:205

Purity/Quality:

97% ^*data from raw suppliers

BENZO[B]FURAN-3-YLACETYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 14-29-34
Safety Statements: 8-23-29-30-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CO2)CC(=O)Cl

Technology Process of Benzo[b]furan-3-ylacetyl chloride

There total 3 articles about Benzo[b]furan-3-ylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64175-51-5
2-(3-benzofuranyl)acetic acid

: 857283-98-8
2-(benzofuran-3-yl)acetyl chloride

Guidance literature:: With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; 1) 0-5 deg C, 30 min; 2) rt, 2 h;
DOI:10.1021/jo9814593

Reference yield:

: 7169-34-8
3-oxo-2,3-dihydrobenzo[b]furan

: 857283-98-8
2-(benzofuran-3-yl)acetyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / toluene; 1,2-dichloro-benzene / 0.33 h / 210 °C / microwave irradiation

2: 98 percent / aq. KOH / ethanol / 1 h / Heating

3: oxalyl chloride; DMF / tetrahydrofuran / 1 h

With potassium hydroxide; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; ethanol; 1,2-dichloro-benzene; toluene;
DOI:10.1021/jm060631p

Reference yield:

: 82156-58-9
benzofuran-3-yl-acetic acid ethyl ester

: 857283-98-8
2-(benzofuran-3-yl)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / aq. KOH / ethanol / 1 h / Heating

2: oxalyl chloride; DMF / tetrahydrofuran / 1 h

With potassium hydroxide; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; ethanol;
DOI:10.1021/jm060631p