(1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Base Information

Chemical Name:(1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester
CAS No.:315179-50-1
Molecular Formula:C₂₀H₃₁N₃O₃
Molecular Weight:361.484
Hs Code.:

Synonyms:(1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Suppliers and Price of (1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

There total 5 articles about (1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 315179-50-1
(1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 7.38 g / N,N-dimethyl-4-aminopyridine / tetrahydrofuran / 24 h / 20 °C

2: 98 percent / H₂ / Pd/C / ethanol / 2 h / 20 °C / 760.05 Torr

3: 22.2 mg / tetrahydrofuran / 12 h / -78 - 20 °C

With dmap; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; 1: Acylation / 2: Catalytic hydrogenation / 3: Substitution;
DOI:10.1021/jo000821m

Reference yield:

: 315179-46-5
((1R,2R)-2-Benzyloxycarbonylamino-cyclohexyl)-carbamic acid benzyl ester

: 315179-50-1
(1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 7.38 g / N,N-dimethyl-4-aminopyridine / tetrahydrofuran / 24 h / 20 °C

2: 98 percent / H₂ / Pd/C / ethanol / 2 h / 20 °C / 760.05 Torr

3: 22.2 mg / tetrahydrofuran / 12 h / -78 - 20 °C

With dmap; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; 1: Acylation / 2: Catalytic hydrogenation / 3: Substitution;
DOI:10.1021/jo000821m

Reference yield:

: 315179-47-6
C₂₂H₂₅N₂O₄C₅H₉O₂

: 315179-50-1
(1R,2R)-2-[N-(2-dimethylaminobenzoyl)amino]cyclohexylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / H₂ / Pd/C / ethanol / 2 h / 20 °C / 760.05 Torr

2: 22.2 mg / tetrahydrofuran / 12 h / -78 - 20 °C

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; 1: Catalytic hydrogenation / 2: Substitution;
DOI:10.1021/jo000821m