5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile

Base Information

Chemical Name:5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile
CAS No.:1155846-73-3
Molecular Formula:C₂₁H₁₁F₃N₆O₂
Molecular Weight:436.353
Hs Code.:

Synonyms:5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile

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Chemical Property of 5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile

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Technology Process of 5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile

There total 1 articles about 5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1155847-36-1
5-{[2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile

: 174180-76-8
3-bromomethylpyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester

: 1155846-73-3
5-{[2-oxo-1-(1H-pyrazolo[3,4-b]pyridine-3-ylmethyl)-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile

Guidance literature:: 5-{[2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}isophthalonitrile; 3-bromomethylpyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; With potassium carbonate; In N,N-dimethyl-formamide; at 19 - 26 ℃; for 16h;

With trifluoroacetic acid; for 0.5h;