Technology Process of 1-<(2,2-dimethyl-1,3-dioxan-5yl)methyl>cytosine
There total 1 articles about 1-<(2,2-dimethyl-1,3-dioxan-5yl)methyl>cytosine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / triethylamine / CH2Cl2 / 1 h / 0 °C
2: 44 percent / cesium carbonate / dimethylformamide / 18 h / 90 °C
With
caesium carbonate; triethylamine;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00062a006
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 88 percent / hydrogen chloride / methanol / 1.25 h / Ambient temperature
2: 66 percent / methanol / Heating
3: 58 percent / triethylamine / dimethylformamide / 1 h / Ambient temperature
With
hydrogenchloride; triethylamine;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00062a006
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 88 percent / hydrogen chloride / methanol / 1.25 h / Ambient temperature
2: 66 percent / methanol / Heating
3: 58 percent / triethylamine / dimethylformamide / 1 h / Ambient temperature
4: 1.) DMSO, dicyclohexylcarbodiimide, dichloroacetic acid, 2.) oxalic acid dihydrate / 1.) RT, 1 h, 2.) DMSO, methanol, RT, 0.5 h
With
hydrogenchloride; dichloro-acetic acid; oxalic acid; dimethyl sulfoxide; triethylamine; dicyclohexyl-carbodiimide;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00062a006