4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide

Base Information

• Chemical Name: 4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide
• CAS No.: 100872-56-8
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.261
• Mol file: 100872-56-8.mol

Synonyms:4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide

Chemical Property of 4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide

Chemical Property:

Purity/Quality:

4-hydroxy-N'-(4-hydroxybenzylidene)benzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide

There total 7 articles about 4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + 4-hydroxybenzoic acid hydrazide (5351-23-5) → 4-hydroxy-N’-[(E)-(4-hydroxyphenyl)methylidene]benzohydrazide (100872-56-8)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2014.03.017

Reference yield: 90.2%

→ 4-hydroxy-[(4-hydroxyphenyl)methylidene]benzohydrazide (100872-56-8)

Guidance literature:

With acetic acid; In ethanol; for 5h; Reflux;

Reference yield: 90.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + 4-hydroxybenzoic acid hydrazide (5351-23-5) → 4-hydroxy-[(4-hydroxyphenyl)methylidene]benzohydrazide (100872-56-8)

Guidance literature:

4-hydroxy-benzaldehyde; With acetic acid; In ethanol; at 20 ℃; for 0.166667h;

4-hydroxybenzoic acid hydrazide; In ethanol; at 20 ℃; for 12h;

DOI:10.1016/j.bmcl.2017.04.007

upstream raw materials:

4-hydroxy-benzaldehyde

4-hydroxybenzoic acid hydrazide

methyl 4-hydroxylbenzoate

4-aminobenzohydrazide

Downstream raw materials:

C₁₅H₁₀N₂O₃S₂

2,5-bis-(4-hydroxyphenyl)-1,3,4-oxadiazole