{2-[3-(Trifluoromethoxy)phenyl]ethyl}amine

Base Information

Chemical Name:{2-[3-(Trifluoromethoxy)phenyl]ethyl}amine
CAS No.:467461-10-5
Molecular Formula:C9H10F3NO
Molecular Weight:205.18
Hs Code.:2922199090
Mol file:467461-10-5.mol

Synonyms:2-(3-Trifluoromethoxyphenyl)ethylamine;3-Trifluoromethoxyphenethylamine;

Suppliers and Price of {2-[3-(Trifluoromethoxy)phenyl]ethyl}amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
{2-[3-(Trifluoromethoxy)phenyl]ethylamine
100mg
$ 65.00

Labseeker
2-(3-(trifluoromethoxy)phenyl)ethanamine 95
10g
$ 2108.00

American Custom Chemicals Corporation
2-(3-TRIFLUOROMETHOXY-PHENYL)-ETHYLAMINE 95.00%
10G
$ 3401.48

American Custom Chemicals Corporation
2-(3-TRIFLUOROMETHOXY-PHENYL)-ETHYLAMINE 95.00%
5G
$ 2592.98

Total 15 raw suppliers

Chemical Property of {2-[3-(Trifluoromethoxy)phenyl]ethyl}amine

Chemical Property:

Vapor Pressure:0.19mmHg at 25°C
Refractive Index:1.471
Boiling Point:210.635 °C at 760 mmHg
Flash Point:81.189 °C
PSA：35.25000
Density:1.234 g/cm³
LogP:2.78670

Purity/Quality:

97% ^*data from raw suppliers

{2-[3-(Trifluoromethoxy)phenyl]ethylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of {2-[3-(Trifluoromethoxy)phenyl]ethyl}amine

There total 4 articles about {2-[3-(Trifluoromethoxy)phenyl]ethyl}amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 108307-56-8
2-[3-(trifluoromethoxy)phenyl]ethanenitrile

: 467461-10-5
2-(3-(trifluoromethoxy)phenyl)ethan-1-amine

Guidance literature:: 2-[3-(trifluoromethoxy)phenyl]ethanenitrile; With borane-THF; In tetrahydrofuran; at 0 - 20 ℃; for 17.6667h; Heating / reflux;

With methanol; In tetrahydrofuran; at 0 - 5 ℃; for 1.5h; Heating / reflux;

Reference yield: 42.0%

: 1-(2-nitrovinyl)-3-(trifluoromethoxy)benzene

: 467461-10-5
2-(3-(trifluoromethoxy)phenyl)ethan-1-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 4h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.7b01113

Reference yield:

: 52771-21-8,50823-91-1
3-(trifluoromethoxy)benzaldehyde

: 467461-10-5
2-(3-(trifluoromethoxy)phenyl)ethan-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; ammonium acetate / 3 h / Reflux

2: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; ammonium acetate; acetic acid; In tetrahydrofuran;
DOI:10.1021/acs.jmedchem.7b01113