C₂₀H₂₃N₃O₆

Base Information

• Chemical Name: C₂₀H₂₃N₃O₆
• CAS No.: 1257585-70-8
• Molecular Formula: C₂₀H₂₃N₃O₆
• Molecular Weight: 401.419
• Mol file: 1257585-70-8.mol

Synonyms:C₂₀H₂₃N₃O₆

Chemical Property of C₂₀H₂₃N₃O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₃N₃O₆

There total 4 articles about C₂₀H₂₃N₃O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H18N2O3 (1257692-52-6) + 6-chlorocarbonyl-nicotinic acid methyl ester (169124-35-0) → C20H23N3O6 (1257585-70-8)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; for 48h;

Reference yield:

4-(tert-Butoxycarbonylaminomethyl)benzoic acid (33233-67-9) → C20H23N3O6 (1257585-70-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 1,1'-carbonyldiimidazole / dichloromethane / 1 h / 20 °C

2: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

3: sodium hydrogencarbonate / water; tetrahydrofuran / 48 h / 20 °C

With hydrogenchloride; sodium hydrogencarbonate; 1,1'-carbonyldiimidazole; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water;

Reference yield:

p-aminomethylbenzoic acid (56-91-7) → C20H23N3O6 (1257585-70-8)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate / water / 3 h / 20 - 40 °C / Cooling with ice

2: 1,1'-carbonyldiimidazole / dichloromethane / 1 h / 20 °C

3: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

4: sodium hydrogencarbonate / water; tetrahydrofuran / 48 h / 20 °C

With hydrogenchloride; sodium hydrogencarbonate; potassium carbonate; 1,1'-carbonyldiimidazole; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water;

upstream raw materials:

p-aminomethylbenzoic acid

4-(tert-Butoxycarbonylaminomethyl)benzoic acid

C₁₂H₁₈N₂O₃

6-chlorocarbonyl-nicotinic acid methyl ester

Downstream raw materials:

C₁₉H₂₃N₅O₅

Refernces