2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate

Base Information

• Chemical Name: 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate
• CAS No.: 1616867-96-9
• Molecular Formula: C₃₄H₅₉NO₇
• Molecular Weight: 593.845
• Mol file: 1616867-96-9.mol

Synonyms:2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate

Chemical Property of 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate

There total 3 articles about 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-(3-pentadecy-8-en-1-yl)phenoxyethanamine + (tri(ethylene glycol) monomethyl ether) succinic acid ester → 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate (1616867-96-9)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 25 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c4tb00134f

Reference yield:

tert-butyl (2-(3-pentadecylphenoxy)ethyl)carbamate (1616867-95-8) → 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate (1616867-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 1 h / 25 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 25 °C / Inert atmosphere

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;

DOI:10.1039/c4tb00134f

Reference yield:

triethylene glucol monomethyl ether (112-35-6,95507-80-5) → 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-oxo-4-((2-(3-pentadecylphenoxy)ethyl)amino)butanoate (1616867-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 24 h / 25 °C / Inert atmosphere

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 25 °C / Inert atmosphere

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1039/c4tb00134f

upstream raw materials:

tert-butyl (2-(3-pentadecylphenoxy)ethyl)carbamate

triethylene glucol monomethyl ether