Technology Process of C36H47N4O7P
There total 4 articles about C36H47N4O7P which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 7h;
DOI:10.1246/bcsj.71.1887
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 86 percent / LDA / tetrahydrofuran; hexane / 5 h / -60 - 20 °C / further reagent DBU, DMAP
2: 1.) hydrogen, 2.) NaHCO3 / 1.) 10percent Pd-C / 1.) methanol, 2 h, 2.) water, acetone, 0 deg C, 1 h , room temperature, 5 h
3: DCC / ethyl acetate / 3 h / 0 °C
4: DIEA, HOBt-H2O / CH2Cl2 / 7 h / 0 - 20 °C
With
hydrogen; sodium hydrogencarbonate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; hexane; dichloromethane; ethyl acetate;
DOI:10.1246/bcsj.71.1887
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) hydrogen, 2.) NaHCO3 / 1.) 10percent Pd-C / 1.) methanol, 2 h, 2.) water, acetone, 0 deg C, 1 h , room temperature, 5 h
2: DCC / ethyl acetate / 3 h / 0 °C
3: DIEA, HOBt-H2O / CH2Cl2 / 7 h / 0 - 20 °C
With
hydrogen; sodium hydrogencarbonate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
dichloromethane; ethyl acetate;
DOI:10.1246/bcsj.71.1887
