Ethyl 2-(3-methylpiperidin-4-yl)acetate

Base Information

Chemical Name:Ethyl 2-(3-methylpiperidin-4-yl)acetate
CAS No.:173186-92-0
Molecular Formula:C₁₀H₁₉NO₂
Molecular Weight:185.266
Hs Code.:
DSSTox Substance ID:DTXSID801242497

Synonyms:ethyl 2-(3-methylpiperidin-4-yl)acetate;173186-92-0;ethyl 3-methyl-piperidin-4-acetate;(3-Methylpiperidin-4-yl)acetic acid ethyl ester;SCHEMBL8577121;DTXSID801242497;CS-0185172;4-Piperidineacetic acid, 3-methyl-, ethyl ester;A1-08487

Suppliers and Price of Ethyl 2-(3-methylpiperidin-4-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(3-Methylpiperidin-4-yl)acetic acid ethyl ester 95%
2.500g
$ 1816.00

A1 Biochem Labs
(3-Methylpiperidin-4-yl)aceticacidethylester 95%
2.5 g
$ 1100.00

Total 4 raw suppliers

Chemical Property of Ethyl 2-(3-methylpiperidin-4-yl)acetate

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:185.141578849
Heavy Atom Count:13
Complexity:170

Purity/Quality:

97% ^*data from raw suppliers

(3-Methylpiperidin-4-yl)acetic acid ethyl ester 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC1CCNCC1C

Technology Process of Ethyl 2-(3-methylpiperidin-4-yl)acetate

There total 6 articles about Ethyl 2-(3-methylpiperidin-4-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-ethoxycarbonylmethyl-3-methylpiperidine-1-carboxylic acid tert-butyl ester

: 173186-92-0
(3-methylpiperidin-4-yl)acetic acid ethyl ester

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 20 ℃; for 39h;

Reference yield:

: 107418-97-3
ethyl (2E)-(1-benzyl-3-methylpiperidin-4-ylidene)acetate

: 173186-92-0
(3-methylpiperidin-4-yl)acetic acid ethyl ester

Guidance literature:: With 20% palladium hydroxide-activated charcoal; hydrogen; In ethanol; at 20 ℃; for 20h;

Reference yield:

: 181269-69-2
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate

: 173186-92-0
(3-methylpiperidin-4-yl)acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 1 h / 20 °C / Cooling with ice

1.2: 2.5 h / 50 °C

2.1: palladium 10% on activated carbon; hydrogen / ethanol / 18 h / 20 °C

3.1: hydrogenchloride / ethyl acetate / 39 h / 20 °C

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; ethanol; ethyl acetate;