Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Base Information

Chemical Name:Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester
CAS No.:849372-31-2
Molecular Formula:C₂₆H₄₁NO₅Si
Molecular Weight:475.701
Hs Code.:

Synonyms:Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Suppliers and Price of Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

There total 7 articles about Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3aS,6R,6aS)-6-((tert-butyldimethylsilyloxy)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol

: 849372-31-2
Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / n-BuLi / tetrahydrofuran

2: 78 percent / PCC; 4 Angstroem MS / CH₂Cl₂

3: NaBH(OAc)3; 4 Angstroem MS; AcOH / CH₂Cl₂ / 40 °C

4: KHCO₃ / ethyl acetate; H₂O

With n-butyllithium; 4 Angstroem MS; sodium tris(acetoxy)borohydride; potassium hydrogencarbonate; acetic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; water; ethyl acetate; 1: Wittig reaction;
DOI:10.3987/COM-04-S(P)45

Reference yield:

: 849372-21-0
(4R,5R)-1-(2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)-2-(tert-butyldimethylsilyloxy)ethan-1-one

: 849372-31-2
Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH(OAc)3; 4 Angstroem MS; AcOH / CH₂Cl₂ / 40 °C

2: KHCO₃ / ethyl acetate; H₂O

With 4 Angstroem MS; sodium tris(acetoxy)borohydride; potassium hydrogencarbonate; acetic acid; In dichloromethane; water; ethyl acetate;
DOI:10.3987/COM-04-S(P)45

Reference yield:

: 849372-15-2
5-O-tert-butyldimethylsilyl-2,3-O-isopropylidene-D-lyxono-1,4-lactone

: 849372-31-2
Allyl-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-((4S,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl]-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / DIBAL-H / toluene / -40 °C

2: 77 percent / n-BuLi / tetrahydrofuran

3: 78 percent / PCC; 4 Angstroem MS / CH₂Cl₂

4: NaBH(OAc)3; 4 Angstroem MS; AcOH / CH₂Cl₂ / 40 °C

5: KHCO₃ / ethyl acetate; H₂O

With n-butyllithium; 4 Angstroem MS; sodium tris(acetoxy)borohydride; diisobutylaluminium hydride; potassium hydrogencarbonate; acetic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; water; ethyl acetate; toluene; 2: Wittig reaction;
DOI:10.3987/COM-04-S(P)45