(R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one

Base Information

Chemical Name:(R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one
CAS No.:1567403-71-7
Molecular Formula:C₂₁H₁₉N₃O
Molecular Weight:329.401
Hs Code.:

Synonyms:(R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one

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Technology Process of (R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one

There total 2 articles about (R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 860772-43-6
(E)-1-(1-methyl-1H-imidazole-2-yl)-3-phenylprop-2-en-1-one

: 120-72-9
indole

: 1567403-71-7
(R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one

Guidance literature:: With C₃₈H₃₈IrN₄O₂⁽¹⁺⁾*F₆P^(1-); In tetrahydrofuran; at 20 ℃; for 16h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja4132505

Reference yield:

: 120-72-9
indole

: 99802-91-2
2-cinnamoyl-1-methyl-1H-imidazole

: 1567403-71-7
(R)-3-(1H-indol-3-yl)-1-(1-methyl-1H-imidazol-2-yl)-3-phenylpropan-1-one

: C₂₁H₁₉N₃O

Guidance literature:: With SGVIKPDMKIKLKMEGNVNGYAFVIEGEGEGKPYDGTNTINLEVKEGAPLPFSYDILTTAFAYGNRAFTKYPDDIPNYFKQSFPEGYSWERTMTFEDKGIVKVKSDISLEEDSFIYEIYLKGENFPPNGPVMQKKTTGWDASTERMYVRDGVLKGDVKHKLLLEGGGYYRVDFKTIYRAKKAVKLPDYHFVDHRIECLNHDKDHNKVTVYESAVARNSTD; copper(II) nitrate; In aq. buffer; at 4 ℃; for 48h; pH=5; pH-value; Reagent/catalyst; enantioselective reaction; Enzymatic reaction;
DOI:10.1021/acscatal.9b02896