(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Base Information

Chemical Name:(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine
CAS No.:897931-60-1
Molecular Formula:C₃₅H₄₄N₃O₆P
Molecular Weight:633.725
Hs Code.:

Synonyms:(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Suppliers and Price of (S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

There total 6 articles about (S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 897931-58-7
(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethyl-4-methoxypyrimidin-2(1H)-one

: 897931-60-1
(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Guidance literature:: With ammonia; In methanol; at 110 ℃; for 16h;
DOI:10.1135/cccc20060579

Reference yield:

: 897931-54-3
5-ethyl-4-methoxypyrimidin-2(1H)-one

: 897931-60-1
(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / Cs₂CO₃ / dimethylformamide / 10 h / 75 °C

2: 79 percent / NaH / tetrahydrofuran / 26 h / 25 - 40 °C

3: 50 percent / NH₃ / methanol / 16 h / 110 °C

With ammonia; sodium hydride; caesium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc20060579

Reference yield:

: 897931-56-5
(S)-5-ethyl-1-[2-hydroxy-3-(triphenylmethoxy)propyl]-4-methoxypyrimidin-2(1H)-one

: 897931-60-1
(S)-1-{2-[(diisopropoxyphosphoryl)methoxy]-3-(triphenylmethoxy)propyl}-5-ethylcytosine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / NaH / tetrahydrofuran / 26 h / 25 - 40 °C

2: 50 percent / NH₃ / methanol / 16 h / 110 °C

With ammonia; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1135/cccc20060579