2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide

Base Information

• Chemical Name: 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide
• CAS No.: 1015198-49-8
• Molecular Formula: C₁₂H₁₇NO₂S
• Molecular Weight: 239.338
• Mol file: 1015198-49-8.mol

Synonyms:2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide

Chemical Property of 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide

There total 1 articles about 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

ortho-anisaldehyde (135-02-4) + (R)-2-methylpropane-2-sulfinamide (196929-78-9) → 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide (1015198-49-8)

Guidance literature:

With pyridinium p-toluenesulfonate; magnesium sulfate; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/chem.201102655

Reference yield: 94.0%

2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide (1015198-49-8) + allyl bromide (106-95-6) → C15H23NO2S (1015198-68-1)

Guidance literature:

With indium; sodium bromide; In water; at 20 ℃; for 12h; optical yield given as %de; diastereoselective reaction; Saturated solution;

DOI:10.1021/ol8001514

Reference yield: 92.0%

bromoacetic acid tert-butyl ester (5292-43-3) + 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide (1015198-49-8) → C18H29NO4S (1272676-11-5)

Guidance literature:

bromoacetic acid tert-butyl ester; 2-methylpropane-2-sulfinic acid [1-(2-methoxyphenyl)methylidene]amide; With samarium diiodide; In tetrahydrofuran; at -78 ℃; for 2.16667h; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1007/s11426-010-4180-z

upstream raw materials:

ortho-anisaldehyde

(R)-2-methylpropane-2-sulfinamide

Downstream raw materials:

C₁₅H₂₃NO₂S

(R)-N-((S,E)-2-benzylidene-1-(2-methoxyphenyl)-4-phenylbut-3-ynyl)-2-methylpropane-2-sulfinamide

C₁₄H₂₁NO₂S

C₁₃H₁₉F₂NO₂S