2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Base Information

Chemical Name:2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride
CAS No.:1202237-87-3
Molecular Formula:C₁₇H₁₅FN₂O₂*ClH
Molecular Weight:334.778
Hs Code.:
Mol file:1202237-87-3.mol

Synonyms:2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Suppliers and Price of 2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95%
5g
$ 972.00

Crysdot
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95%
250mg
$ 139.00

Crysdot
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95%
100mg
$ 87.00

Crysdot
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95%
1g
$ 347.00

Chemenu
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95%
1g
$ 327.00

Chemenu
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95%
5g
$ 916.00

Alichem
(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride
5g
$ 1029.00

Total 8 raw suppliers

Chemical Property of 2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Chemical Property:

Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-(2-Amino-3-(3-fluorophenyl)propyl)isoindoline-1,3-dionehydrochloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

There total 3 articles about 2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1201923-48-9
1,1-dimethylethyl {(1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-[(3-fluorophenyl)methyl]ethyl}carbamate

: 1202237-87-3
2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 12h;

Reference yield:

: 114873-01-7,114873-11-9
N-Boc-3-fluoro-L-phenylalanine

: 1202237-87-3
2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: borane-THF / tetrahydrofuran / 3 h / 0 - 20 °C

2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 2 h / 20 °C

3: hydrogenchloride / 1,4-dioxane; methanol / 2 h / 20 °C

With hydrogenchloride; borane-THF; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1,4-dioxane; methanol;

Reference yield:

: 944470-56-8,1199781-37-7
tert-butyl [(1S)-1-(3-fluorobenzyl)-2-hydroxyethyl]carbamate

: 1202237-87-3
2-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 2 h / 20 °C

2: hydrogenchloride / 1,4-dioxane; methanol / 2 h / 20 °C

With hydrogenchloride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1,4-dioxane; methanol;