N1,N1,3,5-tetramethylbenzene-1,4-diamine

Base Information

• Chemical Name: N1,N1,3,5-tetramethylbenzene-1,4-diamine
• CAS No.: 27746-08-3
• Molecular Formula: C₁₀H₁₆N₂
• Molecular Weight: 164.25
• European Community (EC) Number: 890-631-5
• Mol file: 27746-08-3.mol

Synonyms:27746-08-3;N1,N1,3,5-tetramethylbenzene-1,4-diamine;1-N,1-N,3,5-tetramethylbenzene-1,4-diamine;4-N,4-N,2,6-tetramethylbenzene-1,4-diamine;SCHEMBL9638465;CBA74608;AKOS004117816;BB 0261295;CS-0118029;2,6,N',N'-Tetramethyl-benzene-1,4-diamine;EN300-116284;F70473;N-(4-Amino-3,5-dimethylphenyl)-n,n-dimethylamine

Chemical Property of N1,N1,3,5-tetramethylbenzene-1,4-diamine

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 164.131348519
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1N)C)N(C)C

Technology Process of N1,N1,3,5-tetramethylbenzene-1,4-diamine

There total 4 articles about N1,N1,3,5-tetramethylbenzene-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5,N,N-tetramethylaniline (4913-13-7) → N1,N1,3,5-tetramethylbenzene-1,4-diamine (27746-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; conc. HCl / 2 h / -10 °C

2: SnCl₂ / ethanol / 1.5 h / Heating

With hydrogenchloride; tin(ll) chloride; sodium nitrite; In ethanol;

DOI:10.1039/b617576g

Reference yield:

4-nitroso-N,N-3,5-tetramethylaniline hydrochloride → N1,N1,3,5-tetramethylbenzene-1,4-diamine (27746-08-3)

Guidance literature:

With hydrogenchloride; tin; In water; at 70 ℃;

DOI:10.1039/b809793c

Reference yield:

2,6-dimethyl-4-dimethylamino(nitroso)benzene (29785-94-2) → N1,N1,3,5-tetramethylbenzene-1,4-diamine (27746-08-3)

Guidance literature:

With tin(ll) chloride; In ethanol; for 1.5h; Heating;

DOI:10.1039/b617576g

upstream raw materials:

2,6-dimethyl-4-dimethylamino(nitroso)benzene

3,5,N,N-tetramethylaniline

Downstream raw materials:

methyl-[1,4]benzoquinone-4-(4-dimethylamino-2,6-dimethyl-phenylimine)

(4-Imino-3,5-dimethyl-cyclohexa-2,5-dienylidene)-dimethyl-ammonium

(3,5-Dimethyl-4-oxo-cyclohexa-2,5-dienylidene)-dimethyl-ammonium

2,6,N',N'-Tetramethyl-N-[1-(4-nitro-phenyl)-meth-(E)-ylidene]-benzene-1,4-diamine