N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

Base Information

Chemical Name:N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine
CAS No.:328238-65-9
Molecular Formula:C₂₂H₂₄N₆O₈S
Molecular Weight:532.534
Hs Code.:

N<sup>2</sup>-[(cyanoethoxy)carbonyl]-2'-deoxy-O<sup>6</sup>-[2-(phenylsulfonyl)ethyl]guanosine

Synonyms:N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

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Chemical Property of N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

Chemical Property:

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Technology Process of N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

There total 5 articles about N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [6-(2-Benzenesulfonyl-ethoxy)-9-((2R,4S,5R)-4-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-carbamic acid 2-cyano-ethyl ester

: 328238-65-9
N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

Guidance literature:: With methanol; In dichloromethane; for 0.333333h;
DOI:10.1002/1522-2675(20001220)83:12<3198::AID-HLCA3198>3.0.CO;2-Q

Reference yield:

: 187674-25-5
2'-deoxy-O⁶-<2-(phenylsulfonyl)ethyl>guanosine

: 328238-65-9
N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂ / 0.33 h

2: CH₂Cl₂ / 6 h

3: 0.26 g / MeOH / CH₂Cl₂ / 0.33 h

With pyridine; methanol; In dichloromethane;
DOI:10.1002/1522-2675(20001220)83:12<3198::AID-HLCA3198>3.0.CO;2-Q

Reference yield:

: 6-(2-Benzenesulfonyl-ethoxy)-9-((2R,4S,5R)-4-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-ylamine

: 328238-65-9
N²-[(cyanoethoxy)carbonyl]-2'-deoxy-O⁶-[2-(phenylsulfonyl)ethyl]guanosine

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 6 h

2: 0.26 g / MeOH / CH₂Cl₂ / 0.33 h

With methanol; In dichloromethane;
DOI:10.1002/1522-2675(20001220)83:12<3198::AID-HLCA3198>3.0.CO;2-Q