(R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

Base Information

Chemical Name:(R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole
CAS No.:1442445-51-3
Molecular Formula:C₂₀H₁₉Cl₂N₃
Molecular Weight:372.297
Hs Code.:

Synonyms:(R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

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Chemical Property of (R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

Chemical Property:

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Technology Process of (R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

There total 5 articles about (R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1442445-50-2
(R)-tert-butyl 4-(1-(1-(2,4-dichlorophenyl)ethyl)-1H-indazol-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

: 1442445-51-3
(R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield:

: 1442445-49-9
(R)-6-bromo-1-(1-(2,4-dichlorophenyl)ethyl)-1H-indazole

: 1442445-51-3
(R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; toluene / 18 h / 100 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; trifluoroacetic acid; In dichloromethane; water; toluene;

Reference yield:

: 1442445-48-8
(S)-2,4-dichloro-1-(1-chloroethyl)benzene

: 1442445-51-3
(R)-1-(1-(2,4-dichlorophenyl)ethyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / 1-methyl-pyrrolidin-2-one / 0.17 h / Heating

2: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; toluene / 18 h / 100 °C / Inert atmosphere

3: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; caesium carbonate; trifluoroacetic acid; In 1-methyl-pyrrolidin-2-one; dichloromethane; water; toluene;