(3-methyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-1,2-diyl)dimethanediyl bis(cyclohexylcarbamate)

Base Information

Chemical Name:(3-methyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-1,2-diyl)dimethanediyl bis(cyclohexylcarbamate)
CAS No.:91523-59-0
Molecular Formula:C₂₉H₃₉N₃O₄
Molecular Weight:493.646
Hs Code.:

Synonyms:1,2-bis(hydroxymethyl)-5,6-dihydro-3-methylpyrrolo<2,1-a>isoquinoline bis(cyclohexylcarbamate)

Suppliers and Price of (3-methyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-1,2-diyl)dimethanediyl bis(cyclohexylcarbamate)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (3-methyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-1,2-diyl)dimethanediyl bis(cyclohexylcarbamate)

Chemical Property:

Vapor Pressure:2.4E-20mmHg at 25°C

Purity/Quality:

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Technology Process of (3-methyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-1,2-diyl)dimethanediyl bis(cyclohexylcarbamate)

There total 2 articles about (3-methyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-1,2-diyl)dimethanediyl bis(cyclohexylcarbamate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 3173-53-3
Cyclohexyl isocyanate

: 91523-57-8
1,2-bis(hydroxymethyl)-5,6-dihydro-3-methylpyrrolo<2,1-a>isoquinoline

: 91523-59-0
1,2-bis(hydroxymethyl)-5,6-dihydro-3-methylpyrrolo<2,1-a>isoquinoline bis(cyclohexylcarbamate)

Guidance literature:: With triethylamine; In tetrahydrofuran; for 7h;
DOI:10.1021/jm00376a017

Reference yield:

: 53927-34-7
dimethyl 5,6-dihydro-3-methylpyrrolo<2,1-a>isoquinoline-1,2-dicarboxylate

: 91523-59-0
1,2-bis(hydroxymethyl)-5,6-dihydro-3-methylpyrrolo<2,1-a>isoquinoline bis(cyclohexylcarbamate)

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / LiAlH₄ / CH₂Cl₂; diethyl ether / 1 h / Ambient temperature

2: 47 percent / triethylamine / tetrahydrofuran / 7 h

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jm00376a017