Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester
CAS No.:912352-07-9
Molecular Formula:C₂₈H₃₈O₈S
Molecular Weight:534.671
Hs Code.:

Synonyms:Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Suppliers and Price of Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

There total 10 articles about Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 912352-01-3
(R)-7-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-heptane-1,2-diol

: 98-59-9
p-toluenesulfonyl chloride

: 912352-07-9
Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 12h;
DOI:10.1016/j.tetlet.2006.07.043

Reference yield:

: 912351-95-2
6-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-hexanal

: 912352-07-9
Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / t-BuOK / dimethylsulfoxide / 1 h / 0 °C

2: 41 percent / S,S-Jacobsen catalyst / H₂O / 12 h / 20 °C

3: 71 percent / Et₃N / CH₂Cl₂ / 12 h / 0 °C

With potassium tert-butylate; triethylamine; (S,S)-(salen)manganese; In dichloromethane; water; dimethyl sulfoxide;
DOI:10.1016/j.tetlet.2006.07.043

Reference yield:

: 912351-99-6
(3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-5-(5-oxiranyl-pentyl)-tetrahydro-furo[2,3-d][1,3]dioxole

: 912352-07-9
Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 41 percent / S,S-Jacobsen catalyst / H₂O / 12 h / 20 °C

2: 71 percent / Et₃N / CH₂Cl₂ / 12 h / 0 °C

With triethylamine; (S,S)-(salen)manganese; In dichloromethane; water;
DOI:10.1016/j.tetlet.2006.07.043