2-Chloro-6-methylpyridine-3-boronic acid

Base Information

• Chemical Name: 2-Chloro-6-methylpyridine-3-boronic acid
• CAS No.: 536693-95-5
• Molecular Formula: C₆H₇BClNO₂
• Molecular Weight: 171.391
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID00376752
• Wikidata: Q72454975
• Mol file: 536693-95-5.mol

Synonyms:536693-95-5;2-CHLORO-6-METHYLPYRIDINE-3-BORONIC ACID;(2-chloro-6-methylpyridin-3-yl)boronic acid;2-Chloro-6-methylpyridin-3-ylboronic acid;2-CHLORO-6-METHYLPYRIDINE-3-BORONICACID;2-CHLORO-6-PICOLINE-3-BORONIC ACID;SCHEMBL1922455;DTXSID00376752;ANQOEORPINPUEB-UHFFFAOYSA-N;BBL101535;MFCD03411563;STL555331;AKOS006277520;AB14145;FD10157;Pridine-2-chloro-6-methyl-3-boronicacid;AS-48824;A7808;CS-0174070;FT-0646298;EN300-6495378;J-508975

Chemical Property of 2-Chloro-6-methylpyridine-3-boronic acid

Chemical Property:

• Vapor Pressure: 3.76E-05mmHg at 25°C
• Refractive Index: 1.55
• Boiling Point: 338.7 °C at 760 mmHg
• PKA: 6.85±0.58(Predicted)
• Flash Point: 158.6 °C
• PSA: 53.35000
• Density: 1.347 g/cm³
• LogP: -0.27680
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 171.0258363
• Heavy Atom Count: 11
• Complexity: 136

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-6-methylpyridine-3-boronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: B(C1=C(N=C(C=C1)C)Cl)(O)O

Technology Process of 2-Chloro-6-methylpyridine-3-boronic acid

There total 1 articles about 2-Chloro-6-methylpyridine-3-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (2-chloro-6-methylpyridin-3-yl)boronic acid (536693-95-5) + C18H15B3Cl3N3O3

Guidance literature:

Reference yield: 74.0%

methyl 2-(4'-bromophenyl)-quinoline-4-carboxylate (350997-62-5) + (2-chloro-6-methylpyridin-3-yl)boronic acid (536693-95-5) → methyl 2-(4-(2-chloro-6-methylpyridin-3-yl)phenyl)quinoline-4-carboxylate

Guidance literature:

With dipotassium hydrogenphosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; Reflux;

DOI:10.1021/acs.jmedchem.7b01862

Reference yield: 51.0%

(2-chloro-6-methylpyridin-3-yl)boronic acid (536693-95-5) + 4'-Bromopropiophenone (10342-83-3) → 1-(4-(2-chloro-6-methylpyridin-3-yl)phenyl)propan-1-one

Guidance literature:

With dipotassium hydrogenphosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 130 ℃; for 1.5h; Microwave irradiation;

DOI:10.1021/acs.jmedchem.7b01862

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 536693-95-5 2-CHLORO-6-METHYLPYRIDINE-3-BORONIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send