O-Methyl-L-threonine

Base Information

Chemical Name:O-Methyl-L-threonine
CAS No.:4144-02-9
Molecular Formula:C5H11NO3
Molecular Weight:133.147
Hs Code.:2922500090
European Community (EC) Number:690-841-5
UNII:OAI4PJX6XS
DSSTox Substance ID:DTXSID20195962,DTXSID701031342
Nikkaji Number:J669.036J
Wikidata:Q27285544
ChEMBL ID:CHEMBL1234983
Mol file:4144-02-9.mol

Synonyms:O-methyl threonine;O-methyl threonine, (L-Thr)-isomer

Suppliers and Price of O-Methyl-L-threonine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
O-Methyl-L-threonine
1g
$ 373.00

TRC
O-Methyl-L-threonine
100mg
$ 70.00

SynQuest Laboratories
O-Methyl-L-threonine
1 g
$ 44.00

SynQuest Laboratories
O-Methyl-L-threonine
250 mg
$ 16.00

SynQuest Laboratories
O-Methyl-L-threonine
5 g
$ 192.00

Matrix Scientific
(2S,3R)-2-Amino-3-methoxybutanoic acid
5g
$ 270.00

Matrix Scientific
(2S,3R)-2-Amino-3-methoxybutanoic acid
25g
$ 810.00

Matrix Scientific
(2S,3R)-2-Amino-3-methoxybutanoic acid
10g
$ 406.00

Crysdot
H-Thr(Me)-OH 98%
25g
$ 602.00

Crysdot
H-Thr(Me)-OH 98%
10g
$ 301.00

Total 61 raw suppliers

Chemical Property of O-Methyl-L-threonine

Chemical Property:

Vapor Pressure:0.008mmHg at 25°C
Melting Point:214-216 °C
Refractive Index:1.461
Boiling Point:248 °C at 760 mmHg
PKA:2.12±0.10(Predicted)
Flash Point:103.8 °C
PSA：72.55000
Density:1.143 g/cm³
LogP:0.13350
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Sparingly)
XLogP3:-3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:133.07389321
Heavy Atom Count:9
Complexity:104

Purity/Quality:

97% ^*data from raw suppliers

O-Methyl-L-threonine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

Useful:

Canonical SMILES:CC(C(C(=O)O)N)OC
Isomeric SMILES:C[C@H]([C@@H](C(=O)O)N)OC
Uses O-Methyl-L-threonine can be used as photoresists.

Technology Process of O-Methyl-L-threonine

There total 18 articles about O-Methyl-L-threonine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 85918-01-0,115201-03-1
N-Trt-Thr

: 2076-53-1,2076-57-5,4144-02-9,4385-90-4,34223-42-2,88642-93-7,104195-79-1,104195-80-4
O-methyl-L-threonine

Guidance literature:: With acetic acid; In ethanol; for 24h; Ambient temperature;
DOI:10.1016/S0040-4020(01)88549-5

Reference yield:

: 4144-14-3
methyl (2S,3R)-2-{[(benzyloxy)carbonyl]amino}-3-methoxybutanoate

: 4144-02-9
O-methyl-L-threonine

Guidance literature:: Multi-step reaction with 2 steps

1: aq. LiOH / tetrahydrofuran

2: H₂ / Pd/BaSO₄

With lithium hydroxide; hydrogen; Pd-BaSO₄; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2004.12.082