BOC-PHE-N-CARBOXYANHYDRIDE

Base Information

Chemical Name:BOC-PHE-N-CARBOXYANHYDRIDE
CAS No.:142955-51-9
Molecular Formula:C15H17 N O5
Molecular Weight:291.304
Hs Code.:
European Community (EC) Number:689-013-6
DSSTox Substance ID:DTXSID501144371
Nikkaji Number:J519.067C
Wikidata:Q76416261
Mol file:142955-51-9.mol

Synonyms:boc-l-phenylalaninen-carboxyanhydride;BOC-PHE-N-CARBOXYANHYDRIDE;Boc-Phe-NCA;N-tert-Butoxycarbonyl-L-phenylalanine N-carboxylic anhydride;BOC--PHENYLALANINE NCA

Suppliers and Price of BOC-PHE-N-CARBOXYANHYDRIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-tert-Butyl4-benzyl-2,5-dioxooxazolidine-3-carboxylate 97%
1g
$ 465.00

American Custom Chemicals Corporation
BOC-L-PHENYLALANINE-N-CARBOXYANHYDRIDE 95.00%
0.25G
$ 680.00

Total 12 raw suppliers

Chemical Property of BOC-PHE-N-CARBOXYANHYDRIDE

Chemical Property:

Boiling Point:370.3±25.0 °C(Predicted)
PKA:-3.07±0.40(Predicted)
PSA：72.91000
Density:1.270±0.06 g/cm3(Predicted)
LogP:2.44950
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:291.11067264
Heavy Atom Count:21
Complexity:434

Purity/Quality:

98% ^*data from raw suppliers

(S)-tert-Butyl4-benzyl-2,5-dioxooxazolidine-3-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C(C(=O)OC1=O)CC2=CC=CC=C2
Isomeric SMILES:CC(C)(C)OC(=O)N1[C@H](C(=O)OC1=O)CC2=CC=CC=C2

Technology Process of BOC-PHE-N-CARBOXYANHYDRIDE

There total 4 articles about BOC-PHE-N-CARBOXYANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 927190-29-2
(+/-)-N,N-bis(tert-butoxycarbonyl)phenylalanine

: 142955-51-9
4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: With pyridine; thionyl chloride; N,N-dimethyl-formamide; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1039/c39920000812

Reference yield: 82.0%

: 927190-29-2
(+/-)-N,N-bis(tert-butoxycarbonyl)phenylalanine

: 142955-51-9
4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid tert-butyl ester

: 142955-48-4,149838-63-1
C₁₉H₂₆FNO₅

Guidance literature:: With pyridine; trifluoro-[1,3,5]triazine; In dichloromethane; at -30 ℃; for 1.5h;
DOI:10.1039/c39920000812

Reference yield: 80.4%

: 113568-21-1
(BOC)2Phe-OH

: 142955-48-4
(BOC)2Phe-F

: 142955-51-9
N-butoxycarbonyl-L-phenylalanine anhydride

Guidance literature:: With pyridine; trifluoro-[1,3,5]triazine; In dichloromethane; at -30 - -20 ℃; for 1h; Yields of byproduct given;
DOI:10.1021/jo00067a067