4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate

Base Information

• Chemical Name: 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate
• CAS No.: 301232-42-8
• Molecular Formula: C₂HF₃O₂*C₁₅H₂₀F₂N₂O
• Molecular Weight: 396.357

Synonyms:4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate

Chemical Property of 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate

Chemical Property:

Purity/Quality:

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Technology Process of 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate

There total 1 articles about 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBOP) + (3,4-difluorophenyl)acetic acid (658-93-5) + 4-(N-ethylamino)-1-tert-butoxycarbonylpiperidine (264905-39-7) → 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate (301232-42-8)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

Reference yield:

2-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)-2-(cyclohexyl)acetic acid,4-methoxybenzyl ester + 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate (301232-42-8) → 2-(R)-(3-(S)-(4-(N-((3,4-Difluorobenzyl)carbonyl)-N-ethylamino)-piperidin-1-yl)methyl-4-(S)-phenyl-pyrrolidin-1-yl)-2-(cyclohexyl)acetic acid

Guidance literature:

upstream raw materials:

(3,4-difluorophenyl)acetic acid

4-(N-ethylamino)-1-tert-butoxycarbonylpiperidine

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