[(2S)-1,4-dioxan-2-yl]methanamine

Base Information

Chemical Name:[(2S)-1,4-dioxan-2-yl]methanamine
CAS No.:1337470-52-6
Molecular Formula:C₅H₁₁NO₂
Molecular Weight:117.148
Hs Code.:
European Community (EC) Number:827-323-7

Synonyms:(S)-c-[1,4]Dioxan-2-yl-methylamine;[(2S)-1,4-dioxan-2-yl]methanamine;1337470-52-6;(2S)-1,4-Dioxane-2-methanamine;SCHEMBL5257989;CS-0183411;EN300-1699492

Suppliers and Price of [(2S)-1,4-dioxan-2-yl]methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
(S)-C-[1,4]Dioxan-2-yl-methylamine 97%
1g
$ 298.00

J&W Pharmlab
(S)-C-[1,4]Dioxan-2-yl-methylamine 97%
500mg
$ 198.00

J&W Pharmlab
(S)-C-[1,4]Dioxan-2-yl-methylamine 97%
250mg
$ 149.00

J&W Pharmlab
(S)-C-[1,4]Dioxan-2-yl-methylamine 97%
50mg
$ 98.00

AK Scientific
(S)-c-[1,4]Dioxan-2-yl-methylamine
500mg
$ 569.00

Total 4 raw suppliers

Chemical Property of [(2S)-1,4-dioxan-2-yl]methanamine

Chemical Property:

Boiling Point:190.3±15.0 °C(Predicted)
Density:1.034±0.06 g/cm3(Predicted)
XLogP3:-1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:117.078978594
Heavy Atom Count:8
Complexity:67.4

Purity/Quality:

97% ^*data from raw suppliers

(S)-C-[1,4]Dioxan-2-yl-methylamine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(CO1)CN
Isomeric SMILES:C1CO[C@H](CO1)CN

Technology Process of [(2S)-1,4-dioxan-2-yl]methanamine

There total 5 articles about [(2S)-1,4-dioxan-2-yl]methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1170702-78-9
[(2R)-1,4-dioxane-2-yl]methyl methanesulfonate

: 1337470-52-6
(S)-(1,4-dioxan-2-yl)methanamine

Guidance literature:: With ammonia methyl alcohol; In dichloromethane; at 80 ℃; for 12h; Cooling with ice;

Reference yield:

: 1569298-19-6
(S)-2-(azidomethyl)-1,4-dioxane

: 1337470-52-6
(S)-(1,4-dioxan-2-yl)methanamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; Inert atmosphere;

Reference yield:

: 406913-93-7,143669-41-4
[(2S)-1,4-dioxan-2-yl]methanol

: 1337470-52-6
(S)-(1,4-dioxan-2-yl)methanamine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 5 h / 0 - 20 °C

2: sodium azide; sodium iodide; sodium hydrogencarbonate / N,N-dimethyl-formamide / 20 °C

3: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / Inert atmosphere

With sodium azide; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; triethylamine; sodium iodide; In methanol; dichloromethane; N,N-dimethyl-formamide;